aspg-3-2444-1791419434 20261008003034 American Scientific Publishing Group admin@americaspg.com American Scientific Publishing Group Fusion: Practice and Applications FPA 2770-0070 2692-4048 2024 14 2 Madhu Sudhan H. V. CMR University (CMRU), Bangalore, India S. Saravana Kumar CMR University (CMRU), Bangalore, India Depression is one of the common psychological disorders that affects many people all over the world. The primary typical behavior of depression is persistent low mood, and it is one of the main reasons for disability worldwide. Due to the lack of awareness, treatment, and social stigma, it is leading to suicide and self-harm. It is necessary to identify the depression at a very initial stage to overcome further complications that may lead to suicide. In recent years, certain studies have been done on identifying depression through Machine Learning and Deep Learning techniques. Electroencephalogram (EEG) can be used to detect depression since it is easy to record and non-invasive. The current paper focuses on developing an algorithm that will use the brain signals received through EEG and predict the person as Healthy or with Major Depressive Disorder (MDD) with the help of CNN through an asymmetry matrix, which achieved an accuracy of 89.5%, and it outperformed the previous traditional models. The current study shows that depression detection through EEG is one of the efficient techniques for detecting depression at its early stages. 2024 109 118 2444 https://creativecommons.org/licenses/by/4.0/ 10.54216/FPA.140209 https://www.americaspg.com/journal/3/article/2444 https://www.americaspg.com/storage/71706019852.pdf