aspg-3-3681-1791417577 20261007235937 American Scientific Publishing Group admin@americaspg.com American Scientific Publishing Group Fusion: Practice and Applications FPA 2770-0070 2692-4048 2025 19 2 K. Satyanarayana Murthy Computer Science and System Engineering, AU-TDR-HUB, Andhra University, Visakhapatnam, India; Department of Information Technology, ANITS (A), Visakhapatnam, India Suribabu Korada Scientist-E, NSTL(DRDO), Visakhapatnam, India In medical diagnosis and prognosis, symptoms provided by patients play a critical role in identifying diseases. Machine learning offers a powerful approach to analyzing and predicting illnesses based on these symptoms. In particular, classification algorithms are widely used to analyze input data and predict disease outcomes. A key factor in effective classification is the selection of relevant attributes, which directly affects the accuracy of the prediction. This research emphasizes the importance of proper feature extraction techniques in the context of disease prediction using biomedical signal analysis. Effective analysis requires both the extraction of critical features and the elimination of irrelevant data. The aim of this study is to explore existing approaches to disease prediction based on biomedical signal analysis. We focus on feature extraction from pre-processed data, which aids in distinguishing between different biomedical signals recorded by medical devices. Our objective is to identify biomedical cues that differentiate various health conditions. Examples of such signals include electroencephalogram (EEG), electrocardiogram (ECG), and electrogastrogram (EGG). Understanding how these signals differ between healthy and diseased states is crucial for accurate disease prediction. This research investigates diseases such as heart disease, kidney failure, and lung infections, considering how variations in biomedical signals can be used to predict the likelihood of severe illness. We continue to seek advancements in predicting and mitigating future health risks 2025 315 327 3681 https://creativecommons.org/licenses/by/4.0/ 10.54216/FPA.190223 https://www.americaspg.com/journal/3/article/3681 https://www.americaspg.com/storage/71742557790.pdf