aspg-21-4189-1791472393 20261008151313 American Scientific Publishing Group admin@americaspg.com American Scientific Publishing Group International Journal of Neutrosophic Science IJNS 2692-6148 2690-6805 2025 26 4 Alkan Özkan Department of Mathematics, Faculty of Arts and Sciences, I˘gdır University, I˘gdır, 76000, Turkey Florentin Smarandache University of New Mexico, Mathematics, Physics and Natural Sciences Division 705 Gurley Ave., Gallup, NM 87301, USA ٍSeyda Yazgan TUB˙ITAK Science High School, Kocaeli, Turkey Salem Saleh Department of Mathematics, Hodeidah University, Hodeidah, Yemen Ebru Yesil Department of Mathematics, Faculty of Arts and Sciences, I˘gdır University, I˘gdır, 76000, Turkey This paper introduces and systematically studies new classes of mappings and set-theoretic structures in the context of neutrosophic soft topological structures. In particular, this study introduces and examines neutrosophic soft semi closed and semi open sets, generalized semi-mappings, and semi-continuous generalized mappings, highlighting their interrelationships and key topological properties The neutrosophic soft generalized semi-closure and semi-interior operators are also formulated, and their principal algebraic and topological characteristics are derived. These developments generalize and unify several existing notions in classical, fuzzy, and neutrosophic soft topologies. Unlike previous studies, this work provides a comprehensive mapping-based approach that clarifies how generalized semi-properties behave under neutrosophic soft transformations. The findings not only extend the theoretical foundations of NST but also open potential directions for modeling and analyzing uncertainty in advanced topological systems. 2025 327 347 4189 https://creativecommons.org/licenses/by/4.0/ 10.54216/IJNS.260428 https://www.americaspg.com/journal/21/article/4189 https://www.americaspg.com/storage/01763812342.pdf