Fusion: Practice and Applications FPA 2692-4048 2770-0070 10.54216/FPA https://www.americaspg.com/journals/show/2246 2018 2018 Department of Computer Science, Thanthai Periyar Govt. Arts and Science College (Autonomous), Tiruchirappalli, India Anita Madona. M. Department of Computer Science, Thanthai Periyar Govt. Arts and Science College (Autonomous), Tiruchirappalli, India. Paneer Arokiaraj. S. Glaucoma is a condition where the eyes of human beings are infected due to retinal damage which could result in loss of vision. It generally occurs due to prolonged pressure on the eye and affects the optic nerve if not treated at the earliest stage. However, it is hard for even experts to detect it at the earlier stage. Hence numerous image processing techniques were applied to identify Glaucoma in retinal eyes. The profound purpose of the work is to propose a pre-processing console to remove outliers in the Glaucoma retinal Fundus images using Denoising techniques of pre-processing to enhance the prediction using image pre-processing and computer vision techniques. The model was created with three stages including applying the denoising model using the Median Filtering for Edge Preservation, Contrast Limited Adaptive Histogram Equalization (CLAHE) and optimizing by eliminating irrelevant features using the Black Widow Optimization model and finally evaluating the performance of denoising techniques using accuracy-based predictions. The results showed that after performing a combination of denoising and optimizing techniques, the image quality was enhanced with 97% outperforming the existing models. 2024 2024 93 104 10.54216/FPA.140108 https://www.americaspg.com/articleinfo/3/show/2246