Fusion: Practice and Applications FPA 2692-4048 2770-0070 10.54216/FPA https://www.americaspg.com/journals/show/3668 2018 2018 Department of Computer Science and Engineering , Dr.M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India admin admin Department of Computer Science and Engineering , Dr.M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India Geetha. S. Department of Computer Science and Engineering , Dr.M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India Victo Sudha George. G. Glaucoma is a dangerous eye illness that greatly reduces the sharpness of a person's vision. If not caught early enough, this retinal disorder can damage the optic nerve head (ONH) and cause permanent blindness. Automated glaucoma diagnosis now has tool support thanks to recent advances in deep learning besides the convenience of computing resources. The low reliability of generic convolutional neural networks has prevented their widespread usage in medical procedures, even if deep learning has improved illness diagnosis using medical pictures. While there has been a rise in the use of deep learning for glaucoma classification, very few studies have tested whether or not the models are easy to understand and interpret, which bodes well for their future use. Medical picture feature extraction using Vision Transformers is showcased in this study utilising an EvoTransform: Advanced Evolutionary Algorithm Integration in Transformer Networks named as (EvoTAEA). Combining the powers of Convolutional Neural Networks with Vision Transformers, the suggested EAT Former architecture takes advantage of their data pattern recognition in addition adaptability capabilities. The classification accuracy is enhanced by using the Wild Geese Migration Optimizer (WGMO) to fine-tune the parameters of the proposed feature extraction. The design makes use of new parts, such as the Multi-Scale Region Aggregation, Global and Local Interaction, and Enhanced EA based Transformer blocks with Feed-Forward networks. For dynamically simulating non-standard places, it also presents the Modulated Deformable MSA module. Important components of the Vision Transformer (ViT) model are covered in the study, including patch-based processing, Multi-Head Attention mechanism, and positional context inclusion. In order to give an inductive bias, it presents the Multi-Scale Region Aggregation module, which combines data from several receptive fields. The MSA-based global module is improved by the Global and Local Interaction module, which adds a local path for extracting discriminative local info. An approach to glaucoma diagnosis that integrates ResNet-50, DenseNet-201, and Xception is suggested in the study. Two publicly available datasets, ORIGA and ACRIMA, are used to evaluate the trials. This model can help with the automated diagnosis of glaucoma using fundus pictures. 2025 2025 151 169 10.54216/FPA.190212 https://www.americaspg.com/articleinfo/3/show/3668