Journal of Cognitive Human-Computer Interaction JCHCI 2771-1463 2771-1471 10.54216/JCHCI https://www.americaspg.com/journals/show/3998 2021 2021 Department of Information Science and Engineering, HKBK College of Engineering, Bengaluru, India Naheem Naheem Department of Information Science and Engineering, HKBK College of Engineering, Bengaluru, India Adithya. V. Department of Information Science and Engineering, HKBK College of Engineering, Bengaluru, India Dhanush H.. S. Department of Information Science and Engineering, HKBK College of Engineering, Bengaluru, India Harsh Vishwakarma Neuroengineering Informatics (NEI) is an interdisciplinary field combining neuroscience, engineering, data science, and informatics to understand and control neural systems. It leverages advanced technologies like brain-computer interfaces (BCIs), neuroimaging, and artificial intelligence (AI) to decode brain function and drive clinical breakthroughs. BCIs enable direct communication between the brain and devices, aiding individuals with neurological conditions, while neuroimaging methods such as fMRI, EEG, and MEG generate vast data used to uncover neural patterns linked to cognition, emotion, and disease. AI, particularly deep learning, enhances data analysis, enabling disease prediction, personalized treatment, and decision- making insights. NEI also employs neuroinformatics platforms for data sharing and collaboration, advancing innovations like adaptive neuroprosthetics and brain stimulation techniques such as TMS and DBS to treat conditions like epilepsy, Parkinson’s, and depression. Computational neuroscience contributes further by modeling brain functions to explore learning, memory, and decision-making mechanisms. Despite challenges like integrating diverse datasets and ethical concerns around privacy and fair ness, advancements in cloud computing and parallel processing are addressing these issues, accelerating discoveries while ensuring responsible innovation. NEI’s transformative applications ex tend beyond healthcare to rehabilitation, cognitive enhancement, and human-machine integration, reshaping our understanding and interaction with the brain. 2025 2025 56 66 10.54216/JCHCI.100106 https://www.americaspg.com/articleinfo/25/show/3998