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Journal of Intelligent Systems and Internet of Things

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Online: 2690-6791 Print: 2769-786X
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Journal of Intelligent Systems and Internet of Things
Full Length Article

Volume 16Issue 1PP: 223-232 • 2025

An Optimized Convolutional Neural Network for Alzheimer’s disease Detection

Amena Mahmoud 1* ,
Abdulaziz Shehab 2 ,
A. S. Abohamama 3 ,
Esraa Al-Ezaly 4
1Information Systems Department, Faculty of Computer and Information, Kafr Elsheikh University, 33511, Egypt
2Department of Information Systems, College of Computer and Information Sciences, Jouf University, Sa-kaka 72388, Saudi Arabia; Information Systems Department, Faculty of Computer and Informat
3Department of Computer Science, Mansoura University, Mansoura 35516, Egypt; Department of Computer Science, Arab East Colleges, Riyadh 53354, Saudi Arabia
4Information Systems Department, Faculty of Computer and Information, Mansoura University, Mansoura, 35516, Egypt
* Corresponding Author.
Received: October 17, 2024 Revised: January 03, 2025 Accepted: February 05, 2025

Abstract

Alzheimer’s disease (AD) is a serious diseases distressing society. AD is a complex disease associated with many risk factors, such as aging, genetics, head trauma, and vascular disease. AD is also influenced by environmental factors such as heavy metals and trace metals. The pathology of AD, including amyloid-peptide (Aβ) protein, neurofibrillary tangles (NFTs), and synaptic loss, is still unknown. There are many explanations for the causes of AD. Cholinergic dysfunction is a main danger factor for Alzheimer's disease, whereas others believe that abnormalities in the production and treating of Aβ protein are the primary cause. However, there is currently no accepted hypothesis explaining the pathogenesis of AD. Magnetic resonance imaging is used to diagnose Alzheimer's disease. Our new AD pathogenesis showed 99.77% accuracy with 0.2% efficiency loss and outperformed VGG16, MobileNet2, and Inception V3 without the Adam optimizer and folder hierarchy.

Keywords

Alzheimer's &nbsp Magnetic&nbsp resonance &nbsp Alzheimer&rsquo s&nbsp disease&nbsp detection Brain&nbsp disease

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Mahmoud, Amena, Shehab, Abdulaziz, Abohamama, A. S., Al-Ezaly, Esraa. "An Optimized Convolutional Neural Network for Alzheimer’s disease Detection." Journal of Intelligent Systems and Internet of Things, vol. Volume 16, no. Issue 1, 2025, pp. 223-232. DOI: https://doi.org/10.54216/JISIoT.160119
Mahmoud, A., Shehab, A., Abohamama, A., Al-Ezaly, E. (2025). An Optimized Convolutional Neural Network for Alzheimer’s disease Detection. Journal of Intelligent Systems and Internet of Things, Volume 16(Issue 1), 223-232. DOI: https://doi.org/10.54216/JISIoT.160119
Mahmoud, Amena, Shehab, Abdulaziz, Abohamama, A. S., Al-Ezaly, Esraa. "An Optimized Convolutional Neural Network for Alzheimer’s disease Detection." Journal of Intelligent Systems and Internet of Things Volume 16, no. Issue 1 (2025): 223-232. DOI: https://doi.org/10.54216/JISIoT.160119
Mahmoud, A., Shehab, A., Abohamama, A., Al-Ezaly, E. (2025) 'An Optimized Convolutional Neural Network for Alzheimer’s disease Detection', Journal of Intelligent Systems and Internet of Things, Volume 16(Issue 1), pp. 223-232. DOI: https://doi.org/10.54216/JISIoT.160119
Mahmoud A, Shehab A, Abohamama A, Al-Ezaly E. An Optimized Convolutional Neural Network for Alzheimer’s disease Detection. Journal of Intelligent Systems and Internet of Things. 2025;Volume 16(Issue 1):223-232. DOI: https://doi.org/10.54216/JISIoT.160119
A. Mahmoud, A. Shehab, A. Abohamama, E. Al-Ezaly, "An Optimized Convolutional Neural Network for Alzheimer’s disease Detection," Journal of Intelligent Systems and Internet of Things, vol. Volume 16, no. Issue 1, pp. 223-232, 2025. DOI: https://doi.org/10.54216/JISIoT.160119
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